Functions & Functional enriment scoring

Gene function terms are collected from The Gene Ontology (GO) and Reactome.

Function score in Q-omics, is based on the GSEA (Gene Set Enrichment Analysis) score.

* GO terms used in Q-omics functions

GO functions in Q-omics, consists of ~7,000 "biological process" terms, each of which contain genes with ≥ 3 and ≤300.

* GSEA scores used in Q-omics function scores

Geneset enrichment analysis (GSEA) score quantifies the over-representation of genes associated with a specific biological function within a ranked list of genes, indicating the functional enrichment of that gene set.

GSEA scores of RNA expression protein abundance or CRISPR efficacy data in given functional categories, are calculated and embedded as function scores for selected list of genes, proteins or CRISPR data.

Functional term search